Novel, Simple, Sensitive and Rapid Spectrophotometric Methods for the Determination of Cardol using Sulfanilamides as New Class of Coupling Reagents

First-ever three spectrophotometric methods using sulfanilamide (SAA), sulfadoxine (SDX) and sulfamethoxazole (SMX), the widely used sulfa drugs as new class of coupling agents for the spectrophotometric determination of cardol, a phenolic compound found in cashew nut shell liquid, a by-product of cashew industry is proposed. The methods are based on the interaction of diazotized sulfa drugs with cardol to produce an orange yellow colored product with a maximum absorption at 440 nm. The color developed was stable up to 6 h. The methods obey Beer’s law. The methods can be successfully employed for the determination of cardol in presence of anions and cations, which do not interfere in the methods.